Acanthocytosis as a predisposing factor for non-ketotic hyperglycaemia induced chorea-ballism

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Acanthocytosis as a predisposing factor for non-ketotic hyperglycaemia induced chorea-ballism.

BACKGROUND Episodic non-ketotic hyperglycaemia in patients with diabetes may be responsible for a syndrome characterised by hemichorea-hemiballism associated with unique radiological features. OBJECTIVE To investigate whether factors other than hyperglycaemia may be responsible for the neurological involvement. METHODS Three patients who developed a persistent chorea-ballism syndrome trigge...

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Diabetic non-ketotic hyperglycaemia presenting as chorea--a case report.

We report a patient with hyperosmolar non-ketotic hyperglycaemia who presented with chorea and septic arthritis on his knee. The chorea resolved completely and quickly with correction of the metabolic disturbance, only to return just as quickly when his metabolic disturbance subsequently deteriorated as a result of overwhelming septicaemia, suggesting coexisting cerebral ischaemia, although the...

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Chorea-ballismus in acute non-ketotic hyperglycaemia.

Diabetic patients during hyperglycaemic crises may present a rare syndrome characterised by a typical triad: unilateral involuntary movements (hemichoreahemiballism), radiological contralateral striatal abnormality, and rapid resolution of symptoms after glycae - mic correction. This study reports a series of patients showing less usual aspects and also discusses the pathophysiology of this cli...

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Chorea-acanthocytosis presenting as dystonia.

The aim of this article is to present two Slovenian chorea-acanthocytosis (ChAc) siblings with an unusual predominantly dystonic ChAc phenotype. For diagnostic purposes, the genomic DNA was screened for VPS13A mutations. Movement disorder was evaluated and scored according to the Dystonia Movement and Disability Scale (DMDS) in order to evaluate the effects of L-dopa on dystonia. Brain imaging ...

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Non-ketotic hyperglycaemic chorea: a SPECT study.

OBJECTIVE To study regional blood flow of the striatum in non-ketotic hyperglycaemic choreic patients. METHODS Brain SPECT was performed with intravenous injection of 20 mCi 99mTc hexamethylpropylene amineoxime in six non-ketotic hyperglycaemic choreic patients and 10 age matched patients with a similar level of hyperglycaemia without chorea as a control. The focal perfusion defects were anal...

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ژورنال

عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry

سال: 2005

ISSN: 0022-3050

DOI: 10.1136/jnnp.2005.067033